Bernabe-Garcia M, Rodriguez-Cruz M, Atilano S, et al. Body composition and body mass index in Duchenne muscular dystrophy: Role of dietary intake. Muscle & nerve 2019;59:295-302
Davidson ZE, Billich NK. Are boys with duchenne muscular dystrophy eating more than they need to? Maybe. Muscle & nerve 2019;59:277-279
INTRODUCTION: In Duchenne muscular dystrophy (DMD) muscle is replaced by adipose tissue. The role of dietary intake (DI) in DMD has not been evaluated. We examined body composition , BMI and adequacy of DI in patients with DMD and evaluated the influence of DI on body composition.
METHODS: Patients (n=101; age 3 to 18 years; BMI 11.8 to 29.5 kg/m(2) ) completed a dietary recall to determine DI and underwent dual-energy x-ray absorptiometry to determine body composition.
RESULTS: Preschool-age and school-age boys with DMD had high total energy intake. Protein intake/kg exceeded recommendations. As age increased, the percentage of boys with abnormal BMI and fat mass increased, while lean mass decreased. Dietary intake did not predict body fat or lean mass.
DISCUSSION: Age dependent changes in BD in boys with DMD may be due to endogenous metabolic factors related to the underlying disease process and to disease-related mobility impairments. This article is protected by copyright. All rights reserved.