Comprehensive Assessment of Cardiac Involvement in Muscular Dystrophies by Cardiac MR Imaging

Rochitte CE, Liberato G, Silva MC. Comprehensive Assessment of Cardiac Involvement in Muscular Dystrophies by Cardiac MR Imaging. Magnetic resonance imaging clinics of North America 2019;27:521-531

Abstract

Muscular dystrophy is a group of genetically inherited diseases with irreversible and progressive muscle loss and is associated with cardiac involvement. Particularly in Duchenne and Becker dystrophies, cardiac disorders are the leading causes of mortality. Cardiovascular magnetic resonance imaging (CMR) can detect even incipient myocardial fibrosis (late gadolinium enhancement), which has prognostic significance in patients with preserved left ventricular function by echocardiogram and before the onset of symptoms. Early detection of cardiac abnormalities by CMR enables early cardioprotective treatment, leading to a better prognosis.

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